Construction materials

A step forward in the quest to develop living building materials and beyond

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Some engineered living materials can combine the strength of ordinary building materials with the responsiveness of living systems. Think of self-healing concrete, paint that changes color when a specific chemical is detected, or a material that could reproduce and fill a crack as it forms. This would revolutionize construction and maintenance, with far-reaching economic and environmental implications.

Seeing this new category of adaptive materials on consumer shelves may be a long way off. Yet early critical research from the University of Minnesota sheds new light on this exciting breakthrough, which holds promise beyond building materials, including biomedical applications.

In one new study in Nature Communication, researchers at the College of Biological Sciences show how to transform silica, a material commonly used in plaster and other building materials, into a self-assembling, dynamic and resilient material.

Currently, the majority of manufactured living materials rely on adding a living component to a material. While this additive approach has its advantages, it falls short of the suction material – a product that grows, self-organizes, and heals. Other researchers managed to engineer a bacteria to produce the target material, but it could only survive under ideal laboratory conditions. This would not be enough in real world applications.

The researchers, led by Claudia Schmidt-Dannert, McKnight Emeritus Professor in the Department of Biochemistry, Molecular Biology and Biophysics, used a well-studied and benign bacteria, Bacillus subtilis, which goes dormant under unfavorable conditions and comes back to life when conditions are favorable for growth. This characteristic made it a strong candidate, as future products would eventually have to be stable on the shelf and easily activated. The research team then designed the bacteria and studied the optimal approach to integrate it into the structure of silica.

“The first time we saw bacteria and silica crosslink and form a rigid material, that was essential. At that point, we knew it was working, ”explains Schmidt-Dannet.

The results provide a framework for the design of new living engineering materials for coatings and coatings, key building materials.

The Schmidt-Danvert research team begins to study new starting materials. “We’re now interested in going beyond silica, using different cells, maybe even multiple cell types, to develop new living modified materials for a range of applications. “

– This press release was originally published on the University of Minnesota website

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